Contrast-enhanced MRI index of diffuse myocardial fibrosis is increased in primary aldosteronism

What is new in contrast enhanced MRI

Automatic Characterization of Myocardial Perfusion in Contrast Enhanced MRI

The use of contrast medium in cardiac MRI allows joining the high-resolution anatomical information provided by standard magnetic resonance with functional information obtained by means of the perfusion of contrast agent in myocardial tissues. The current approach to perfusion MRI characterization is the qualitative one, based on visual inspection of images. Moving to quantitative analysis requ...

Association Between Diffuse Myocardial Fibrosis by Cardiac Magnetic Resonance Contrast-Enhanced T1 Mapping and Subclinical Myocardial Dysfunction in Diabetic Patients

Background—Diabetic patients have increased interstitial myocardial fibrosis on histological examination. Magnetic resonance imaging (MRI) T1 mapping is a previously validated imaging technique that can quantify the burden of global and regional interstitial fibrosis. However, the association between MRI T1 mapping and subtle left ventricular (LV) dysfunction in diabetic patients is unknown. Me...

Quantitative Assessment of Microscopic Fibrosis in Patients with Primary Aldosteronism Using Dynamic Contrast Enhancement

Introduction Primary aldosteronism (PA) is characterized by autonomous production of aldosterone by the adrenal cortex and is considered to stimulate myocardial fibrosis (1). Late gadolinium enhancement (LGE) MRI has been widely used to show the fibrosis of the myocardium in various cardiac diseases (2). Comparing to bulky fibrosis which is readily discernable by focal myocardial regions with v...

Electrical and Myocardial Remodeling in Primary Aldosteronism

OBJECTIVE AND DESIGN Primary aldosteronism (PA) represents the most common cause of secondary hypertension. A higher risk of cardiovascular events has been reported in patients with PA than in otherwise similar patients with essential hypertension (EH). So far, only a few studies investigated the electrocardiographic changes in PA patients compared to EH patients. METHODS To investigate the e...